王鹏

教学育人成果：

科研成果：

1.科研项目

（1）国家自然科学基金青年项目：白屈菜红碱通过RIP1介导线粒体功能障碍在胶质瘤细胞程序性坏死中的作用机（82003793）

（2）浙江省卫生厅项目：mROS-Drp1通路介导线粒体释放在白屈菜红碱致胶质瘤细胞程序性坏死中的机制研究（2021KY201）

（3）温州市科技局项目：基于RIP1/mROS/Drp1途径探讨白屈菜红碱诱导胶质瘤细胞程序性坏死的机制研究（Y2020183）

2.发表论文（具有代表性的5篇）

（1）Wang Peng, Zhang Sun-Dong, Jiao Jiao, Wang Wei, Yu Liang, Zhao Xue-Lian, Wang Li-Tao, Meng Dong, Fu Yu-Jie. ROS -mediated p53 activation by juglone enhances apoptosis and autophagy in vivo and in vitro Toxicology and Applied Pharmacology, 2019, 379,114647.

（2）Wang Peng, Gao Chang, Wang Wei, Yao Li-Ping, Zhang Jing, Zhang, Sun-Dong & Fu Yu-Jie. Juglone induces apoptosis and autophagy via modulation of mitogen-activated protein kinase pathways in human hepatocellular carcinoma cells. Food and Chemical Toxicology, 2018, 116, 40-50.

（3）Wang Peng, Gao Chang, Guo Na, Zhang Sun-Dong, Wang Wei, Yao Li-Ping & Fu Yu-Jie. 2′-O-Galloylhyperin Isolated From Pyrola incarnata Fisch. Attenuates LPS-Induced Inflammatory Response by Activation of SIRT1/Nrf2 and Inhibition of the NF-κB Pathways in Vitro and Vivo. Frontiers in pharmacology, 2018, 9.

（4）Wang Peng, Gao Yi-Meng, Sun Xing, Guo Na, Li Ji, Wang Wei & Fu Yu-Jie. Hepatoprotective effect of 2′-O-galloylhyperin against oxidative stress-induced liver damage through induction of Nrf2/ARE-mediated antioxidant pathway. Food and Chemical Toxicology,2017, 102, 129-142.

（5）Wang Peng, Qiao Qi, Li Ji, Wang Wei, Yao Li-Ping & Fu Yu-Jie. Inhibitory effects of geraniin on LPS-induced inflammation via regulating NF-κB and Nrf2 pathways in RAW 264.7 cells. Chemico-biological interactions, 2016, 253, 134-142.