周洁

教学育人成果：指导学生多次获得省新苗科技创新项目，以指导老师指导学生先后获浙江省互联网+创新创业比赛金奖，国家级挑战杯创新创业比赛铜奖。指导本科生毕业论文多次获得校、院级优秀毕业论文。

1.科研成果：

（1）国家自然科学基金青年项目，非促分裂型FGF-1通过介导氧化应激作用治疗肾病的机制研究，负责人。

（2）浙江省自然科学基金面上项目，长效型 FGF21 改构体的设计及其保护胆汁淤积性肝损伤的作用机制研究，负责人。

2.所获成果（包括科研成果奖、专利、专著等）

3.发表论文（具有代表性的5篇）

（1）Jie Zhou, Xinwei Chen, Qiong Chen, Beibing Pan, Jiaxin Lou, Zhenyu Jia, Yali Du, Wenxin Xu, Lu Zhang, Xin Feng, Lingwei Jin, Mengru Shi, Xiaokun Li, Zhifeng Huang,* and Jian Sun*,Novel Muscle-Homing Peptide FGF1 Conjugate Based on AlphaFold 2 for Type 2 Diabetes Mellitus. ACS Applied Materials & Interfaces,2023(IF=10.63)

（2）Miaojuan Fan，Tongtong Pan, Wei Jing, Jian Sun, Shujun Zhang, Yali Du, Xinwei Chen, Qiong Chen, Guanghui Zhu, Yongping Chen*, Jie Zhou*, FGF4, a new potential regulator in gestational diabetes mellitus. Frontiers in pharmacology,2022(IF=5.87)

（3）Jian Sun, Jiamin Wu, Hui Jin, Te Ying, Wei Jin, Miaojuan Fan, Jianhui Zhou, Hui Chen*, Litai Jin*, Jie Zhou*，Structure-guided design, generation and bioactivity of PEGylated fibroblast growth factor 2 variants for wound healing. Nanoscale. 2020, (IF=7.79)

（4）Jie Zhou#, Xingguang Cai#, Xun Huang, Yuxuan Dai, Lidan Sun, Bo Zhang ,Bo Yang, Haiyan Lin*, Wenlong Huang*, Hai Qian *,A novel glucagon-like peptide-1/glucagon receptor dual agonist exhibits weight-lowering and diabetes-protective effects, European Journal of Medicinal Chemistry,138 (2017) 1158-1169 (IF=6.51)

（5）Jie Zhou, Xue Li, Xiaoyun Zhu, Jian Sun, Qianqian Qiu, Wenlong Huang*, Hai Qian*, Phenylbutazone, a New Long-Acting Agent that can improve the Peptide Pharmacokinetic Based on Serum Albumin as a Drug Carrier, Chemical biology & drug design 2016,6(81):936-45. (IF=2.54)