科研成果： 1. 科研项目 （1）第四届温州医科大学“校优青培养工程”，2020/07-2024/07, 80万，项目负责人，在研； （2）国家自然科学基金，靶向cSH2结构域的新型PLCγ1选择性抑制剂设计、合成及其缓解FGF23 诱导心室重构的药理作用研究，2021/01-2024/12, 56万，第二参与人，在研； （3）国家自然科学基金，D-A-D大共轭π桥结构有机染料的合成及其在太阳能电池中的应用研究，2018/01-2020/12，26万，项目负责人，已结题； （4）浙江省自然科学基金，高光热转换效率有机复合纳米药物的构建及其在乳腺癌上的光热和化疗协同治疗研究，2024/01-2026/12，10万，项目负责人，在研。 2. 所获成果（包括科研成果奖、专利、专著等） 第一发明人授权专利：(1)专利号：CN201810812597.8 (2)专利号：CN201710743454.1 （3）专利号：CN202110213557.3 (4)专利号：CN202011239521.4 (5)专利号：CN202111500553.X （6）专利号：CN202111452179.0 3. 发表论文（具有代表性的5篇） (1) Hongyan Shen#; Binbin Wu#; Qin Zhang; Jiahao Ni; Manshan Liang; Yanlong Liu; Xu-Feng Zang; Shihua Wang; Yun-Yun Quan*; Xiaoxia Ye*; Zu-Sheng Huang*, Acceptor/π-bridge planarization and donor rotation manipulation for designing an NIR-II AIEgen with high photothermal conversion efficiency to enhance cancer phototherapy. Chemical Engineering Journal, 2023, 468, 143726 (IF: 15.1) (2) Yun-Yun Quan#, Tingting Pan#, Zhongda Zhang#, Shihua Wang, Guiyun Wang, Lichao Yu, Ye Wang, Xu-Feng Zang, Fangjun Zhang, Xiaoxia Ye*, Xuebo Pan*, Zu-Sheng Huang*, Three-in-One: Molecular Engineering of D–A–π–A Featured Type I and Type II Near-Infrared AIE Photosensitizers for Efficient Photodynamic Cancer Therapy and Bacteria Killing. Small, 2024, 20, 2402854. (IF: 13.0) (3) Zu-Sheng Huang#; Wenxuan Zhang#; Manshan Liang#; Shihua Wang; Zhongda Zhang; Yongsheng Jiang; Xiaoxia Ye; Longteng Xie; Yun-Yun Quan*, A multifunctional fluorescent probe for sequential detection of hydrogen sulfide and pH in foodstuffs, living cells and mice. Analytical Chimica Acta, 2024, 1299, 342434. (IF: 6.2) (4) Liying Pan#, Shihua Wang#, Mintao Xie, Manshan Liang, Lichao Yu, Bin Du, Xiaoxia Ye, Yanshu Luo*, Yun-Yun Quan*, Zu-Sheng Huang*, Biotin receptor and mitochondria dual targeted AIE photosensitizer for fluorescence imaging guided photodynamic anticancer therapy. Materials & Design, 2023, 235, 112441. (IF: 8.4) (5) Zu-Sheng Huang#, Yun-Yun Quan#, Jia-Jun Mao, Yi-Li Wang, Yuekun Lai, Jing Zheng, Zhong Chen, Kun Wei*, Huaqiong Li*, Multifunctional superhydrophobic composite materials with remarkable mechanochemical robustness, stain repellency, oil-water separation and sound-absorption properties. Chemical Engineering Journal, 2019, 358, 1610-1619. (IF: 15.1) |
