2.所获成果(包括科研成果奖、专利、专著等) (1)赵良才(2/9),基于代谢组学的中药药效评价体系的建立与临床应用,浙江省政府,浙江省科学技术进步奖,二等奖,2016 (2)赵良才(3/7),基于NMR代谢组学对肾癌和常见肾病的早期诊断及药效评价体系建立,浙江省科技厅,浙江省科技进步奖,二等奖,2014 3.发表论文(具有代表性的5篇) (1) Xie J, Yan J, et al. Fibroblast growth factor 21 enhances learning and memory performance in mice by regulating hippocampal L-lactate homeostasis, Int J Biol Macromol, 2024, 25;271:132667 (2) Yan J, Xie J, et al. Fibroblast growth factor 21 protects the liver from apoptosis in a type 1 diabetes mouse model via regulating L-lactate homeostasis, Biomed Pharmacother, 2023, 168:115737. (3) Dong M, Yi Q, et al. A combined metabolomics and molecular biology approach to reveal hepatic injury and underlying mechanisms after chronic l-lactate exposure in mice, Comput Struct Biotechnol J, 2022,25;20:3935-3945. (4) Zhao L, Jiang H, et al. Effects of Fibroblast Growth Factor 21 on Lactate Uptake and Usage in Mice with Diabetes-Associated Cognitive Decline, Mol Neurobiol. 2022 Sep;59(9):5656-5672. (5) Zhao L, Dong M, et al., Metabolomic Analysis Identifies Lactate as an Important Pathogenic Factor in Diabetes-associated Cognitive Decline Rats, Molecular & Cellular Proteomics, 2018.12, 17(12): 2335-2346. |