(1)浙江省自然科学基金:靶向于GRP78的ERS小分子抑制剂苯并氧杂吖庚因类化合物的设计合成及构效关系研究.(主持) (2)浙江省自然科学基金:手性催化剂对映选择性的NMR原位快速分析新方法及其机理研究(主持); (3)浙江省自然科学基金:新型高效手性有机小分子催化亚胺不对称还原研究(主持) (4)浙江省教育厅:雪胆属特有种浙江雪胆的活性成分研究(主持) (5)温州市科技局:有机小分子催化高对映选择性制备药物中间体手性醇研究(主持) (6)温州市科技局:银杏内生真菌的分离及其代谢产物应用研究(主持) (7)温州市科技局:ERS小分子抑制剂PBA类似物的设计合成及对大鼠全脑缺血再灌注的保护作用研究(主持) (8)国家自然科学基金:基于功能化石墨烯液晶的残留偶极耦合定向介质及其应用(参与) |
(1)An integrated network pharmacology and cell metabolomics approach to reveal the role of rhein, a novel PPARα agonist, against renal fibrosis by activating the PPARα–CPT1A axis,Phytomedicine, 2022, 102: 154147. (2)A multifunctional BODIPY based fluorescent probe for hydrogen sulfide detection and photodynamic anticancer therapy in HCT116 colon cancer cell,Dyes and Pigments,2022, vol 197, 109897. (3)Experimental investigation of the anti-soiling performances of differentwettability of transparent coatings: Superhydrophilic, hydrophilic,hydrophobic and superhydrophobic coatings,Solar Energy Materials & Solar Cells, 2021, 225: 111053. (4)Effect of the acceptor and alkyl length in benzotriazole-based donoracceptor-donor type hole transport materials on the photovoltaic performance of PSCs,Dyes and Pigments,2019, vol 164, 407-416. (5)A NIR fluorescent probe for the detection and visualization of hydrogen sulfide in colorectal cancer cell,Sensors and Actuators B: Chemical, 2019, vol.298, 1-7. |